Risk factors for severe RSV disease include :
– Immunodeficient patients
– Chronic Kidney Disease
– Severe Obesity (BMI ≥ 40)
– Chronic Respiratory Diseases (COPD, asthma, bronchiectasis, interstitial lung
diseases, chronic respiratory failure)
– Current smoker
– Chronic Heart Failure – Coronary artery disease
– Diabetes
– Stroke.

Considering the high morbidity and mortality associated with RSV infection among patients with known risk factors and the lack of effective anti-viral therapy, the Superior Health Council recommends vaccination against RSV for :
– At risk persons over 60 years old with at least one risk factor for developing
severe RSV disease (listed above), immunodeficient patients (including patients
with solid cancer or haematologic malignancy, use of immunosuppressive
medications, solid organ transplantation, allogenic HCT) and people living in
nursing homes ;
– All persons over 75 years old, especially those with a risk factor listed above or
frail/pre-frail status.

The recommended dose is one single injection intramuscularly with one of the 2
vaccines available (Arexvy ® or Abrysvo ®).
Considering the pre-COVID seasonality of RSV, September/October are the preferred months to be vaccinated although vaccination may be performed year round.

Plus d’informations : Superior Health Council. Vaccination against RSV for older
adults. Brussels : SHC ; 2024. Report 9837.